[Revvity] pHSense, Internalization에 최적화된 Assay
| 브랜드 | Revvity | |||
|---|---|---|---|---|
제품특징
● 특징 및 장점
Time-Resolved
Detection
Detection
높은 민감도와
낮은 Background
낮은 Background
No-Wash Assay
간편한 Add & Read
Workflow
Workflow
High-Throughput
Ready
Ready
96 well 기반
대량 스크리닝
대량 스크리닝
Validated
Platform
Platform
Antibody, ADC, GPCR
연구에 최적화
연구에 최적화
Broad Cell
Compatibility
Compatibility
부유세포·부착세포
모두 적용 가능
모두 적용 가능
● Typical Workflow
✓ Add & Read! No-Wash 방식으로 빠르고 간편하게 결과를 확인할 수 있습니다.
* ADC, GPCR 등 다양한 Application에 적용 가능
pHSense Applications & Products
ADC Antibody-Drug Conjugate Internalization
Internalization efficiency를 정량적으로 평가
Anti-HER2 antibody and ADCs dose-response
on BT-474 cells
on BT-474 cells
GPCR GPCR Internalization
Ligand-induced receptor internalization 분석
Dulaglutide Dose-Response
on HEK-GLP1R cells
on HEK-GLP1R cells
● ADC
| pHSense probes | 96 wells |
| Eu Fab Anti-Human IgG | 81HUEU1AA |
| Eu Fab Anti-Rabbit IgG | 81PAREU1AA |
| Eu Fab Anti-Mouse IgG1 | 81MO1EU1AA |
| Eu Fab Anti-Mouse IgG2 | 81MO2EU1AA |
*2×96 wells, 10×96 wells 제공
● GPCR
| pHSense probes | 96 wells |
| Eu Fab Anti-Human IgG | 81HUEU1AA |
| Eu Fab Anti-Rabbit IgG | 81PAREU1AA |
| Eu Fab Anti-Mouse IgG1 | 81MO1EU1AA |
| Eu Fab Anti-Mouse IgG2 | 81MO2EU1AA |
| Eu Anti-6His | 81HISEU1AA |
| Eu Anti-FLAG | 81FL1EU1A |
| Eu Anti-HA | 81HAEU1AA |
| Eu SNAP Labeling Reagent | 81SNEU1A |
*2×96 wells, 10×96 wells 제공
● 보조시약
| 1 vial | |
| Human IgG1 Isotype Control | 81HUIGG1NC |
| Human IgG4 Isotype Control | 81HUIGG4NC |
| Mouse IgG1 Isotype Control | 81MOIGG1NC |
| Mouse IgG2a Isotype Control | 81MOIGG2ANC |
| Boost Reagent | 81BOOSTR1 |
| 96 well | |
| pHSense Eu Reader Control Kit | 82RCLEUPEA |
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