줄기세포 연구의 모든 것, Stem Cell Marker


✿ Cell type 별 stem cell marker 종류

Marker Name Cell Type
Blood Vessel
Fetal liver kinase-1 (Flk1) Endothelial
Smooth muscle cell-specific myosin heavy chain Smooth muscle
Vascular endothelial cell cadherin Smooth muscle
Bone-specific alkaline phosphatase (BAP) Osteoblast
Hydroxyapatite Osteoblast
Osteocalcin (OC) Osteoblast
Bone Marrow and Blood
Bone morphogenetic protein receptor (BMPR) Mesenchymal stem and progenitor cells
CD4 and CD8 White blood cell (WBC)
CD34 Hematopoietic stem cell (HSC), satellite, endothelial progenitor
CD34+Sca1+ Lin- profile Mesencyhmal stem cell (MSC)
CD38 Absent on HSC
CD44 Mesenchymal
c-Kit HSC, MSC
Colony-forming unit (CFU) HSC, MSC progenitor
Fibroblast colony-forming unit (CFU-F) Bone marrow fibroblast
Hoechst dye Absent on HSC
Leukocyte common antigen (CD45) WBC
Lineage surface antigen (Lin) HSC, MSC
Differentiated RBC and WBC lineages
Mac-1 WBC
Muc-18 (CD146) Bone marrow fibroblasts, endothelial
Stem cell antigen (Sca-1) HSC, MSC
Stro-1 antigen Stromal (mesenchymal) precursor cells, hematopoietic cells
Thy-1 HSC, MSC
Collagen types II and IV Chondrocyte
Keratin Keratinocyte
Sulfated proteoglycan Chondrocyte
Adipocyte lipid-binding protein (ALBP) Adipocyte
Fatty acid transporter (FAT) Adipocyte
Adipocyte lipid-binding protein (ALBP) Adipocyte
Y chromosome Male cells
Karyotype Most cell types
Albumin Hepatocyte
B-1 integrin Hepatocyte
Pluripotent Stem Cells
Alkaline phosphatase Embryonic stem (ES), embryonal carcinoma (EC)
Alpha-fetoprotein (AFP) Endoderm
Bone morphogenetic protein-4 Mesoderm
Brachyury Mesoderm
Cluster designation 30 (CD30) ES, EC
Cripto (TDGF-1) ES, cardiomyocyte
GATA-4 gene Endoderm
Genesis ES, EC
Germ cell nuclear factor ES, EC
Hepatocyte nuclear factor-4 (HNF-4) Endoderm
Nestin Ectoderm, neural and pancreatic progenitor
Neuronal cell-adhesion molecule (N-CAM) Ectoderm
Pax6 Ectoderm
Stage-specific embryonic antigen-3 (SSEA-3) ES, EC
Stage-specific embryonic antigen-4 (SSEA-4) ES, EC
Stem cell factor (SCF or c-Kit ligand) ES, EC, HSC, MSC
Telomerase ES, EC
TRA-1-60 ES, EC
TRA-1-81 ES, EC
Vimentin Ectoderm, neural and pancreatic progenitor
Skeletal Muscle/Cardiac/Smooth Muscle
MyoD and Pax7 Myoblast, myocyte
Myogenin and MR4 Skeletal myocyte
Myosin heavy chain Cardiomyocyte
Myosin light chain Skeletal myocyte